
Zürich Area, Switzerland

Zürich Area, Switzerland
My primary research interests are in the area of Systems Biology, particularly pathway modelling and in the analysis of complex networks. I have experience in constraint-based modelling of biochemical networks, comparative phylogenetic analysis of genomes and comparative metabolic network analysis.
I am particularly interested in the application of complex network science to various disciplines, in and outside biology.
I look forward to a career of research in an industry or academic setting.
Ph.D. , Systems Biology, Scientific Computing , 2003 — 2008
SELECTED PUBLICATIONS
•“Strategies for efficient disruption of metabolism in M. tb. from network analysis” Mol BioSyst (In press) (2009)
•“Flux balance analysis of biological systems: applications and challenges” Briefings in Bioinformatics 10:435–449 (2009)
•“M. tb. interactome analysis unravels potential pathways to drug resistance” BMC Microbiol 8:230 (2008)
•“targetTB: A target identification pipeline for M. tb. through an interactome, reactome and genome-scale structural analysis” BMC Syst Biol 2:109 (2008)
•“Metabolome based reaction graphs of M. tuberculosis and M. leprae: A comparative network analysis” PLoS ONE 2(9):e881 (2007)
•“Hallmarks of Mycolic Acid Biosynthesis: A Comparative Genomics Study” Proteins. 69:358–368 (2007)
•“Principles and Practices of Pathway Modelling” Current Bioinformatics 1(2):147—160 (2005)
•“Flux Balance Analysis of Mycobacterium tuberculosis: targets for anti-tubercular drugs” PLoS Comput Biol 1:e46 (2005)
B. Tech , Biochemistry, Biochemical Engineering, Food Technology, Chemical Engineering , 1999 — 2003
Thesis: Study of staling and preservation of cereal-legume based fermented foods (2003)
Studied the staling and preservation of dosa, a traditional cereal-legume based fermented food and succeeded in achieving a shelf-life of 3 weeks by using a combination of permitted preservatives and emulsifiers.
1987 — 1999
Systems Biology, Bioinformatics, Algorithms, Scientific Computing, Mathematics